Antioxidants as effective remedies at hepatotoxic action of carbon tetrachloride

Hovnanyan, Karlen and Mamikonyan, Vardan and Margaryan, Anahit and Sargsyan, Kristine and Hovnanyan, Margarita and Karagyozyan, Maria and Karageuzyan, Konstantin (2014) Antioxidants as effective remedies at hepatotoxic action of carbon tetrachloride. Journal of Biophysical Chemistry, 05 (01). pp. 1-4. ISSN 2153-036X

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Official URL: https://doi.org/10.4236/jbpc.2014.51001

Abstract

The liver, as the central metabolic organ, plays an important role in metabolism of carbohydrates, lipids and proteins. In the environment, there are many hepatotoxic xenobiotics. CCl4 is a free radical toxic for organelles of hepatocytes. The presented work was studying the character of ultrastructural changes in CCl4-intoxicated hepatocytes as well as the tissue after treatment by grape seed extract (GSE), α-tocopherol (α-T). As a result of cell bioremediation effect and reactions against corruptive factors, the liver has a high regeneration ability.

Item Type:	Article
Subjects:	European Scholar > Chemical Science
Depositing User:	Managing Editor
Date Deposited:	03 Jan 2023 07:20
Last Modified:	28 Oct 2024 08:13
URI:	http://article.publish4promo.com/id/eprint/799

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