STUDIES ON HEMOPROTEINS AND FREE RADICALS IN VIRCHOWIAN HANSENIASIS AND OTHER BODY DISODERS

Hyperfine structure parameters of hemoproteins in four different body disorders are examined using the electron paramagnetic resonance technique at 77 K and 303 K. g value increases in all types of disorders (i.e. lepromatous leprosy, LL; pulmonary tuberculosis, PTB; burns and leukemia). Spin-spin relaxation time (T2) falls systematically in LL., PTB, burns and leukemia. The value of line width ∆H1/2, is found to highly susceptible in M. leprae infection.

One of the major contribution of the present work is to establish that Fe2+transition metal ions are in low concentration and Cu2+ metal ions are in high concentration in LL hemoprotein samples as compared to normals.