Utilities of Active Methylene Compounds and Heterocycles Bearing Active Methyl or having an Active Methine in the Formation of Heterocyclyl and Heterocyclopyridines (Part III)

This review discusses the work done in the last three decades in our laboratory which describes the use of some common and novel synthesized active methylene compounds as well as heterocycles having active methyl or methine in the syntheses of a wide variety of substituted and condensed pyridines. The used synthetic approaches involves cyclocondensation reactions, ring opening-ring closure, cycloaddition, acid- or base-catalyzed reaction, intermolecular cyclization and self-condensation have been reviewed in this paper. Also, antimicrobial activities of some reported pyridines were discussed.