A SYSTEMATIC REVIEW ON EXTRACTION METHODS, PHARMACOLOGY, PHARMACOKINETICS AND CLINICAL STUDIES OF BIOACTIVE LEAD: 6-GINGEROL

A comparative study has been made between the extraction procedures of {6}-Gingerol based on the instruments, solvents, extraction time and extraction temperature. {6}-Gingerol is the biochemically and therapeutically active amongst various constituents possessed by ginger. The extraction of {6}-Gingerol to obtain high purity compound expresses a challenging and significant task in the pharmaceutical industry because it act as lead compound having anti-tumor activity. Various extraction processes are being used to acquire active constituent from Ginger. A growing body of research suggested that 6-Gingerol has an anti-cancer, anti-inflammatory, analgesic, anti-mutagenic and anti-cholesterol target also. It concluded that pressurized liquid extraction procedure is the best which provide high yield as compared to other extraction processes.