UTILITY OF SOME SULPHA DRUGS IN SYNTHESIS OF NEW BIOLOGICALLY ACTIVE HETEROCYCLIC COMPOUNDS : SYNTHESIS AND ANTICANCER ACTIVITY OF SOME NOVEL THIOSEMICARBAZIDE DERIVATIVES

AHMED, E. M. and TAHA, N. M. and NADY, N. M. (2011) UTILITY OF SOME SULPHA DRUGS IN SYNTHESIS OF NEW BIOLOGICALLY ACTIVE HETEROCYCLIC COMPOUNDS : SYNTHESIS AND ANTICANCER ACTIVITY OF SOME NOVEL THIOSEMICARBAZIDE DERIVATIVES. Al-Azhar Bulletin of Science, 22 (1). pp. 57-68. ISSN 1110-2535

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Abstract

N-(4-(N-(2,6-dimethoxypyrimidin-4-yl)sulfamoyl)phenyl) hydrazine carbothioamide novel thiosemicarbazide (3) was used as starting material for synthesis of some novel Diacetyl hydrazine-carbothioamide (4), 1,3,4-Thiadiazol (7), 1,2-bis(carbothioamide) (9), 3,5-di-oxopyrazolidine (10), oxo-4,5-dihydropyrazole (11), 3,4-dihy-drophthalazine (15) and 3,6-dioxopiperazine (16).Where we found that, 1,2-bis(carbothioamide) (5), 1,2,4-triazole (6), carbamothioyl formohydrazonate (8) have anticancer activity of drug (s) using (E.A.C).

Item Type: Article
Subjects: European Scholar > Medical Science
Depositing User: Managing Editor
Date Deposited: 17 Jul 2023 05:19
Last Modified: 20 Sep 2023 06:47
URI: http://article.publish4promo.com/id/eprint/2153

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